Nurturing Your Liver: 360-Degree Health and Wellness Companion

In the bustling narrative of health and wellness, there’s an unsung hero that often evades the spotlight—your liver. It's the silent toiler, the body's internal janitor, and plays the role of a maestro when it comes to biochemical processing within the human body. Yet, ask yourself when was the last time you considered how to care for this important organ?

Our lifestyle, dietary choices, and environmental factors weigh heavily on our liver health, potentially leading to a myriad of medical conditions. In this exhaustive guide, we'll take a magnifying glass to liver care, exploring why it's so critical to well-being and how you can fortify this core component of your body’s system.

While explicitly untangling the liver's significance can be complex, imagine it as the central processing unit of bodily functions. It metabolises what we consume, filters toxins from the bloodstream, stores essential nutrients, and assists with digestion (1). When the liver's health falters, it sets off a ripple effect of health issues that touch every aspect of our physiology.

Major Takeaway: Your liver's health isn't just about avoiding liver diseases; it's about bolstering overall health and vitality.

The liver is primarily responsible for detoxifying the body (2). Through a process called biotransformation, it neutralises various harmful substances, which are then eliminated from the body. However, when the liver becomes overwhelmed or diseased, it can't function optimally, leading to a toxic build-up in the body.

Major Takeaway: Liver health is imperative for warding off a broad spectrum of diseases.

The liver stores vitamins and minerals, including iron and vitamin B12 (3), which are essential for the production of red blood cells. It also produces bile, which breaks down fats during digestion.

Major Takeaway: Optimal liver function contributes to nutrient availability and smooth digestion.

A healthy liver isn't just a solitary state of well-being; it's a domino effect that impacts numerous bodily systems.

Relationship to the Liver: Conditions that impair liver function can lead to imbalances in cholesterol and triglycerides, raising your risk of heart disease (4).

Relationship to the Liver: The liver regulates blood sugar levels and processes hormones. An unhealthy liver can lead to metabolic syndrome, diabetes, and weight gain (5).

Relationship to the Liver: The liver helps fight infections and clears bacteria from the blood. Liver diseases can weaken the immune system (6).

Relationship to the Liver: When the liver fails, it can result in a condition called hepatic encephalopathy, where toxins build up and affect brain function (7).

We often underestimate the power of day-to-day choices in shaping our health trajectories. Diet and lifestyle are architects that can either erect a fortress around your liver or gradually erode its vitality.

High-fibre foods, like fresh fruits and vegetables, support digestive health and ease the liver's workload (8). Antioxidant-rich foods help protect liver cells from damage (9). Berries, nuts, and green leafy vegetables are among the top foods known for their high antioxidant content, offering a powerful shield against liver cell damage.

Processed foods, high in unhealthy fats and sugars, can lead to fatty liver disease (10). Excessive alcohol consumption is a well-known adversary of the liver (11).

Net fluid balance is crucial for liver health. Dehydration can concentrate toxins in your body, stressing the liver (12).

Regular exercise can reduce fat and inflammation in the liver, mitigating the risk of non-alcoholic fatty liver disease (13).

While no pill can substitute a wholesome lifestyle, there are supplements that can complement your efforts to maintain liver wellness.

Possessing antioxidant and anti-inflammatory properties, milk thistle is a popular choice for liver support (14).

Studies have suggested that vitamin E can reduce liver damage from oxidative stress and hinder fatty liver disease (15).

B-vitamins are catalysts in energy production and liver function, especially vitamin B12 and folic acid (16).

Supports biochemical reactions in the body including glucose regulation and nerve function, which is significant for liver health (17).

Analogous to the car's regular service, the liver too needs periodic check-ups to ensure it's in top condition.

Liver enzyme tests in routine blood work can identify elevated levels that signal liver damage or disease. Beyond these standard assessments, functional medicine offers additional tests to evaluate liver health more comprehensively. These include tests for markers of liver detoxification capacity, oxidative stress levels, and the balance of bile acids, providing a deeper insight into liver function.

Moreover, functional medicine often utilises comprehensive metabolic panels, which can assess the liver's performance in processing proteins, glucose, and fats, alongside evaluating the health of the gallbladder. By integrating these specialised tests, healthcare providers can offer a more holistic view of liver health, identifying potential issues early and tailoring personalised treatment plans.

Ultrasound, computed tomography (CT), or magnetic resonance imaging (MRI) scans can provide detailed images of the liver and aid in diagnosis.

While invasive, a liver biopsy can provide comprehensive insights into the extent of liver damage.

Understanding liver diseases is akin to understanding the antagonistic forces that can assail this vital organ.

The accumulation of fat in the liver, often due to obesity and high cholesterol, is a common precursor to liver inflammation and more severe conditions.

Inflammation of the liver can be caused by a variety of factors, most notably viral infections.

A scarring of the liver tissue, often as a result of chronic inflammation or liver disease, can lead to significant impairment of liver function.

Promoting liver longevity isn't just about quantity of life, but quality. With these insights and strategies in hand, you're well-equipped to begin—or continue—your quest for a liver that hums with vitality.

Get adequate sleep, maintain a healthy weight, and practice stress-reducing techniques like meditation.

Minimise exposure to environmental toxins, and be mindful of medications and their potential liver impact.

Always consult with healthcare professionals before radically changing your diet or supplement regimen, and especially before using any treatment for liver disease.

When liver health has taken a hit, rejuvenation becomes paramount. Holistic approaches and medical interventions can guide you back to liver vitality.

Detoxifying diets, acupuncture, and herbal remedies are possible options to employ to support your liver's natural regeneration processes.

For severe liver damage, treatments like transplantation may become necessary. However, with advancements in medicine, less invasive treatments are also an option.

After liver rejuvenation treatments, post-care support is essential. It includes medication adherence, dietary adjustments, and regular doctor visits.

Adopting a liver-friendly nutritional and lifestyle framework isn't just about the liver. It's a testament to nurturing our entire being.

Focusing on foods that reduce inflammation can benefit the liver and the body overall.

Periodic liver detox diets, rich in detoxifying fruits and vegetables, can give your liver a much-needed pause.

Ensuring a balance of healthy fats and sugars is pivotal for maintaining liver health.

Nature provides an arsenal of herbs and spices that can become your liver's best friends.

The active ingredient curcumin in turmeric is renowned for its anti-inflammatory and antioxidant prowess (18).

Gingerol compounds in ginger can mitigate oxidative stress and may support liver health (19).

Historically used to improve liver function and increase the flow of bile, dandelion root is still a liver favourite today (20).

Your liver is a linchpin of vitality. Understanding its needs and nurturing it with care is a profound gift of health and longevity.

From diet and lifestyle to periodic check-ups and the power of supplements, every choice you make plays a role in the symphony of your liver's health. Take on the mantle of liver stewardship with intention and the promise of a thriving health and wellness narrative.

Written by Amy Morris, BSc (Hons) Nutritional Therapy. Amy has been a nutritional therapist for 12 years, specialising in recent years as a functional medicine nutritional therapist. Women’s health, and pre-diabetes and type 2 diabetes prevention are Amy’s specialist areas. Diagnosed with a chronic condition called endometriosis at age 20, this is what motivated Amy to study nutrition. Amy has been in remission for 6 years now, attributing powerful nutrition, lifestyle and bio-identical hormone strategies she now shares with her clients. https://www.greathealthnaturally.co.uk/

Water for Health Ltd began trading in 2007 with the goal of positively affecting the lives of many. We still retain that mission because we believe that proper hydration and nutrition can make a massive difference to people’s health and quality of life. Click here to find out more.

1) NCBI. (2016, August 22). How does the liver work? Nih.gov; Institute for Quality and Efficiency in Health Care (IQWiG). https://www.ncbi.nlm.nih.gov/books/NBK279393/

2) Columbia Surgery. (2019). The Liver and its Functions | Columbia University Department of Surgery. Columbiasurgery.org. https://columbiasurgery.org/liver/liver-and-its-functions

3) Kalra, A., & Tuma, F. (2023, May 1). Physiology, Liver. National Library of Medicine; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK535438/

‌‌4) El Hadi, H., Di Vincenzo, A., Vettor, R., & Rossato, M. (2020). Relationship between Heart Disease and Liver Disease: A Two-Way Street. Cells, 9(3), 567. https://doi.org/10.3390/cells9030567

5) Cotrozzi, G., Casini Raggi, V., Relli, P., & Buzzelli, G. (1997). Ruolo del fegato nella regolazione del metabolismo glucidico in corso di diabete e di epatopatia cronica [Role of the liver in the regulation of glucose metabolism in diabetes and chronic liver disease]. Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna, 12(2), 84–91.

6) Kubes, P., & Jenne, C. (2018). Immune Responses in the Liver. Annual review of immunology, 36, 247–277. https://doi.org/10.1146/annurev-immunol-051116-052415

7‌) Cleveland Clinic. (2020, April 16). Hepatic Encephalopathy: Types, Causes, Symptoms, Treatment. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/21220-hepatic-encephalopathy

8) Mayo Clinic. (2022, November 4). Dietary Fiber: Essential for a Healthy Diet. Mayo Clinic. https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/fiber/art-20043983

9) Casas-Grajales, S., & Muriel, P. (2015). Antioxidants in liver health. World journal of gastrointestinal pharmacology and therapeutics, 6(3), 59–72. https://doi.org/10.4292/wjgpt.v6.i3.59

1‌‌0) Grinshpan, L. S., Eilat-Adar, S., Ivancovsky-Wajcman, D., Kariv, R., Gillon-Keren, M., & Zelber-Sagi, S. (2024). Ultra-processed food consumption and non-alcoholic fatty liver disease, metabolic syndrome and insulin resistance: A systematic review. JHEP Reports, 6(1), 100964. https://doi.org/10.1016/j.jhepr.2023.100964

‌11) Osna, N. A., Donohue, T. M., Jr, & Kharbanda, K. K. (2017). Alcoholic Liver Disease: Pathogenesis and Current Management. Alcohol research : current reviews, 38(2), 147–161.Janeckova E et al. (2018). The interplay between the liver, the glycocalyx and the hepatic and the systemic endothelial glycocalyx during liver regeneration. J Hepatol. 68(5): S815-16.

12) Ivarsen, P., Greisen, J., & Vilstrup, H. (2001). Acute effects of moderate dehydration on the hepatic conversion of amino nitrogen into urea nitrogen in healthy men. Clinical science (London, England : 1979), 101(4), 339–344.

13) Barrón-Cabrera, E., Soria-Rodríguez, R., Amador-Lara, F., & Martínez-López, E. (2023). Physical Activity Protocols in Non-Alcoholic Fatty Liver Disease Management: A Systematic Review of Randomized Clinical Trials and Animal Models. Healthcare, 11(14), 1992. https://doi.org/10.3390/healthcare11141992

‌14) Surai P. F. (2015). Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives. Antioxidants (Basel, Switzerland), 4(1), 204–247. https://doi.org/10.3390/antiox4010204

15) Qi, X., Guo, J., Li, Y., Fang, C., Lin, J., Chen, X., & Jia, J. (2024). Vitamin E intake is inversely associated with NAFLD measured by liver ultrasound transient elastography. Scientific Reports, 14(1), 2592. https://doi.org/10.1038/s41598-024-52482-w

16) Hanna, M., Jaqua, E., Nguyen, V., & Clay, J. (2022). B Vitamins: Functions and Uses in Medicine. The Permanente journal, 26(2), 89–97. https://doi.org/10.7812/TPP/21.204

17) Bravo, M., Simón, J., González-Recio, I., Martinez-Cruz, L. A., Goikoetxea-Usandizaga, N., & Martínez-Chantar, M. L. (2023). Magnesium and Liver Metabolism Through the Lifespan. Advances in Nutrition, 14(4), 739–751. https://doi.org/10.1016/j.advnut.2023.05.009

18) Hewlings, S. J., & Kalman, D. S. (2017). Curcumin: A Review of Its Effects on Human Health. Foods (Basel, Switzerland), 6(10), 92. https://doi.org/10.3390/foods6100092

1‌9) Alsahli, M. A., Almatroodi, S. A., Almatroudi, A., Khan, A. A., Anwar, S., Almutary, A. G., Alrumaihi, F., & Rahmani, A. H. (2021). 6-Gingerol, a Major Ingredient of Ginger Attenuates Diethylnitrosamine-Induced Liver Injury in Rats through the Modulation of Oxidative Stress and Anti-Inflammatory Activity. Mediators of Inflammation, 2021, 1–17. https://doi.org/10.1155/2021/6661937

2‌0) Pfingstgraf, I. O., Taulescu, M., Pop, R. M., Orăsan, R., Vlase, L., Uifalean, A., Todea, D., Alexescu, T., Toma, C., & Pârvu, A. E. (2021). Protective Effects of Taraxacum officinale L. (Dandelion) Root Extract in Experimental Acute on Chronic Liver Failure. Antioxidants (Basel, Switzerland), 10(4), 504. https://doi.org/10.3390/antiox10040504